Sugar acids and derivatives
![Research Products International Corp NANA [n-Acetylneuraminic acid, Synthetic Sialic Acid], 100 Milligrams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-A10080-0.11.JPG-250.jpg)
Research Products International Corp NANA [n-Acetylneuraminic acid, Synthetic Sialic Acid], 100 Milligrams
Substrate for N-Acetylneuraminic acid aldolase.
Medchemexpress LLC N-Glycolylneuraminic acid | 1113-83-3 | 99.8% | 10 MG
N-Glycolylneuraminic acid is a nonhuman sialic acid molecule, synthesized in pigs but not in humans. It functions as a decoy receptor for N-Glycolylneuraminic acid-binding influenza A viruses (IAVs), making it suitable for research applications.
- Nonhuman sialic acid molecule
- Functions as a decoy receptor for influenza A viruses
- Prevents influenza virus entry into A549 cells in vitro studies
- Available as a white to off-white solid
- For research use only
STA PHARMACEUTICAL US LLC 1-(Fmoc-aminomethyl)-beta-D-galacturonic acid | 1 g | CAS 655246-28-9 | MDL MFCD11974983
1-(Fmoc-aminomethyl)-beta-D-galacturonic acid is a Amino Acid reagent (Subcategory: Sugar AA) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 655246-28-9
- MDL: MFCD11974983
- InChIKey: USLKEBRNVKYNDJ-OMZCGLGVSA-N
- Molecular Weight: 429.425
- Molecular Formula: C22H23NO8
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29329900
- Country Of Origin: China
- IUPAC: (2S,3R,4R,5R,6S)-6-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
- SMILES: O=C([C@H]1O[C@@H](CNC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)[C@H](O)[C@@H](O)[C@H]1O)O
Medchemexpress LLC Protac BET degrader-1 | 2093386-22-0 | 99.4% | 871.90 g/mol | C44H45N11O9 | 1 ML
PROTAC BET Degrader-1 is a proteolysis-targeting chimera that links a Cereblon ligand to a BET-family ligand to promote ubiquitination and proteasomal degradation of BET proteins BRD2, BRD3, and BRD4. It is used in biochemical and cellular assays to investigate BET protein degradation and downstream epigenetic effects.
- Induces selective degradation of BRD2, BRD3, and BRD4 at low nanomolar concentrations.
- Provided as a 10 mM solution in DMSO, 1 mL vial.
- High purity (99.4% by LCMS).
- Molecular formula C44H45N11O9; molecular weight 871.90 g/mol.
- Storage: powder -20°C for long term; in solvent -80°C recommended.
Medchemexpress LLC BSJ-04-122 | 2513289-74-0 | 99.9% | 313.74 g/mol | C15H12ClN5O | 10 MG
BSJ-04-122 is a covalent dual inhibitor of the MAP kinase kinases MKK4 and MKK7 developed for research use. It demonstrates potent enzymatic inhibition (IC50 4 nM for MKK4; 181 nM for MKK7) and is applied in studies of cancer biology and MAPK signaling. The compound is supplied as a solid with high chemical purity and recommended storage conditions for both powder and solution forms.
Sigma Aldrich Fine Chemicals Biosciences MUG Supplement suitable for microbiology | 6160-80-1 | MFCD00036772 | 5VL
MUG Supplement suitable for microbiology | Mol Wt: 352.29 | 6160-80-1 | MFCD00036772 | 5VL
Medchemexpress LLC CMP-Sialic acid (sodium salt) | 1007117-62-5 | 90.8% | 636.43 | 25 MG
CMP-Sialic acid sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. It provides a substrate for Golgi sialyltransferases and is an important sugar nucleotide for the biosynthesis of sialic acid and its conjugates.
- Allosteric inhibitor of UDP-GlcNAc 2-epimerase.
- Provides a substrate for Golgi sialyltransferases.
- Important sugar nucleotide for biosynthesis of sialic acid and its conjugates.
- Appearance: Solid, white to off-white.
- Can be used as a CMAH substrate to detect the formation of Neu5Gc in platelet lysates (at 22.5 μM for 45 min).
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f